Pepsinogen iIhlanganisiwe futhi yafunwa amaseli aphezulu esifundazwe se-oxyntic glandular wesisu, futhi uPepsinogen II uguqulwe futhi wafunwa yisifunda se-pyloric esiswini. Zombili zisebenza kuPepsins ku-tumen yesisu yi-HCL ethethwe amaseli we-Fundaric Parietal cell.

1.Yini i-Pepsinogen II?
I-Pepsinogen II ingenye yamaprotheni amane ahlakaniphile: PG I, PG II, uCathepsin E noD. Pepsinogen II ekhiqizwa ngokuyinhloko ku-mucosa ye-oxytic gland ngokuyinhloko esiswini, i-gastric attrum kanye ne-duodenum. Kuthenjelwe ikakhulukazi ku-lumen yesisu futhi kusakazwa.
2.Yini izakhi ze-pepsinogen?
I-Pepsinogenes iqukethe i-polyppede chain eyodwa ngesisindo samangqamuzana esingaba ngu-42,000 DA. I-Pepsinogens ihlanganiswe futhi yafunwa ngokuyinhloko amaseli aphezulu esigxobo esiswini somuntu ngaphambi kokuguqulwa abe yi-pepsin ye-prefelytic ye-enzyme ye-enzyme esiswini.
3.Yini umehluko phakathi kwePepsin nePepsinogen?
I-Pepsin yi-enzyme yesisu esebenza ukugaya amaprotheni atholakala ekudleni okufakiwe. Amangqamuzana e-Grastric Chief at tepsin njenge-zymogen engasebenzi ebizwa ngokuthi i-Pepsinogen. Amangqamuzana e-Parietal ngaphakathi kwesisu esihlangene esiswini se-hydrochloric acid ehlisa i-PH yesisu.

I-Diagnostic Kit ye-Pepsinogen I / Pepsinogenii (Fleorescence Immuno Assay)Ingabe i-fluorescence immunochrochrographic assay yokutholwa kwe-PGI / PGII ku-serum yomuntu noma i-plasma, kusetshenziselwa ikakhulukazi ukuhlaziya i-gandtic oxyntic gland isifo se-gland emtholampilo.

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