I-Mycoplasma pneumoniae iyimbangela evamile yokutheleleka kwemigudu yokuphefumula, ikakhulukazi ezinganeni nakubantu abadala abasebasha. Ngokungafani namagciwane avamile, i-M. pneumoniae ayinawo udonga lweseli, okwenza ihluke futhi ngokuvamile kube nzima ukuyixilonga. Enye yezindlela eziphumelela kakhulu zokuhlonza ukutheleleka okubangelwa yileli gciwane ukuhlola ama-antibodies e-IgM.

Ama-antibodies e-IgM angama-antibodies okuqala akhiqizwa uhlelo lokuzivikela komzimba ekuphenduleni ukutheleleka. Uma umuntu etheleleke nge-Mycoplasma pneumoniae, umzimba uqala ukukhiqiza ama-antibodies e-IgM zingakapheli isonto noma amabili. Ukuba khona kwala ma-antibodies kungaba uphawu olubalulekile lokutheleleka okusebenzayo ngoba amelela impendulo yokuqala yomzimba yokuzivikela komzimba.

Ukuhlolwa kwama-antibodies e-IgM ku-M. pneumoniae kuvame ukwenziwa ngokuhlolwa kwe-serological. Lokhu kuhlolwa kusiza ukuhlukanisa ukutheleleka kwe-M. pneumoniae kwezinye izifo zokuphefumula, njengegciwane noma amagciwane ajwayelekile njenge-Streptococcus pneumoniae. Ukuhlolwa kwe-IgM okuhle kungasekela ukutholakala kwe-pneumonia engavamile, okuvame ukubonakala ngokuqala kancane kancane kwezimpawu, okuhlanganisa ukukhwehlela okuqhubekayo, umkhuhlane, kanye nokungaphatheki kahle.

Kodwa-ke, imiphumela ye-antibody ye-IgM kumele ihunyushwe ngokucophelela. Kungaba khona imiphumela engamanga, futhi isikhathi sokuhlola sibalulekile. Ukuhlolwa kusenesikhathi kakhulu kungaveza imiphumela emibi ngoba ama-antibodies e-IgM athatha isikhathi ukuvela. Ngakho-ke, odokotela bavame ukucabangela umlando wesiguli kanye nezimpawu kanye nemiphumela yelabhorethri ukuze benze ukuxilongwa okunembile.

Ekuphetheni, ukuhlolwa kwama-antibodies e-M. pneumoniae IgM kudlala indima ebalulekile ekuxilongeni izifo zokuphefumula. Ukuqonda lokhu kusabela komzimba kungasiza abahlinzeki bezempilo ukuthi banikeze ukwelashwa okufika ngesikhathi nangokufanele, ekugcineni kuthuthukise imiphumela yesiguli. Njengoba ucwaningo luqhubeka, singathola okwengeziwe ngendima edlalwa yila ma-antibodies ekulweni nezifo zokuphefumula.