Ukwelashwa kokutheleleka nge-Hp 

Isitatimende 17:Umkhawulo wesilinganiso sokwelapha sezinqubo zomugqa wokuqala wezinhlobo ezibucayi kufanele okungenani kube u-95% weziguli ezelashwe ngokwe-protocol set analysis (PP), kanti umkhawulo wesilinganiso sokwelashwa ngamabomu (ITT) kufanele ube u-90% noma ngaphezulu. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 18:I-Amoxicillin ne-tetracycline ziphansi futhi zizinzile. Ukumelana ne-Metronidazole ngokuvamile kuphakeme emazweni ase-ASEAN. Ukumelana ne-clarithromycin bekulokhu kukhuphuka ezindaweni eziningi futhi kwehlise izinga lokuqedwa kokwelashwa okuphindwe kathathu okujwayelekile. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: N/A)

Isitatimende 19:Uma izinga lokumelana ne-clarithromycin liyi-10% kuya ku-15%, libhekwa njengenani eliphakeme lokumelana, futhi indawo ihlukaniswe yaba indawo ephezulu yokumelana nendawo ephansi yokumelana. (Izinga Lobufakazi: Maphakathi; Izinga Elinconyiwe: N/A)

Isitatimende 20:Ezimweni eziningi zokwelapha, isifundo se-14d silungile futhi kufanele sisetshenziswe. Inkambo yokwelashwa emfushane ingamukelwa kuphela uma kufakazelwe ukuthi ifinyelela ngokuthembekile umkhawulo wesilinganiso sokwelapha esingu-95% nge-PP noma umkhawulo wesilinganiso sokwelapha esingu-90% ngokuhlaziywa kwe-ITT. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 21:Ukukhethwa kwezinketho zokwelashwa ezinconyiwe zomugqa wokuqala kuyahlukahluka ngendawo, indawo, kanye namaphethini okumelana nama-antibiotic eyaziwa noma alindelwe iziguli ezizimele. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 22:Uhlu lwemithi yokwelapha yomugqa wesibili kufanele lufake ama-antibiotics angakaze asetshenziswe ngaphambili, njenge-amoxicillin, i-tetracycline, noma ama-antibiotics angazange akhuphule ukungezwani komzimba. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 23:Inkomba eyinhloko yokuhlola ukuthambekela kwemithi elwa namagciwane ukwenza ukwelashwa okusekelwe ekuzweleni, okwamanje okwenziwa ngemva kokuhluleka komugqa wesibili wokwelapha. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile) 

Isitatimende 24:Lapho kungenzeka khona, ukwelashwa okufanele kusekelwe ekuhlolweni kokuzwela. Uma ukuhlolwa kokuba sengozini kungenzeki, izidakamizwa ezimelana nezidakamizwa emhlabeni wonke akufanele zifakwe, futhi izidakamizwa ezimelana nezidakamizwa kancane kufanele zisetshenziswe. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

Isitatimende 25:Indlela yokukhulisa izinga lokuqeda i-Hp ngokwandisa umphumela we-antisecretory we-PPI idinga i-CYP2C19 genotype esekelwe kumsingathi, ngokukhuphula umthamo we-PPI we-metabolic ophezulu noma ngokusebenzisa i-PPI ethintwa kancane yi-CYP2C19. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

Isitatimende 26:Lapho kukhona ukumelana ne-metronidazole, ukwenyusa umthamo we-metronidazole ufike ku-1500 mg/d noma ngaphezulu nokwelula isikhathi sokwelashwa sibe yizinsuku eziyi-14 kuzonyusa izinga lokwelapha lokwelashwa okuphindwe kane nge-expectorant. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

Isitatimende 27:Ama-probiotics angasetshenziswa njengendlela yokwelapha ehambisanayo ukuze kuncishiswe ukusabela okubi nokuthuthukisa ukubekezelelana. Ukusetshenziswa kwama-probiotics kanye nokwelashwa okujwayelekile kungase kuphumele ekwenyukeni okufanele kwamazinga okuqeda. Nokho, lezi zinzuzo azizange ziboniswe njengezindleko eziphansi. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: sibuthakathaka)

Isitatimende 28:Isixazululo esivamile ezigulini ezingazwani ne-penicillin ukusetshenziswa kokwelapha okuphindwe kane nge-expectorant. Ezinye izinketho zincike kuphethini yendawo yokuba sengozini. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

Isitatimende 29:Izinga lokutheleleka kabusha lonyaka le-Hp elibikwe amazwe ase-ASEAN lingu-0-6.4%. (Izinga lobufakazi: medium) 

Isitatimende 30:I-dyspepsia ehlobene ne-Hp iyabonakala. Ezigulini ezine-dyspepsia ezinokutheleleka kwe-Hp, uma izimpawu ze-dyspepsia zikhululeka ngemva kokuba i-Hp iqedwe ngempumelelo, lezi zimpawu zingabhekwa ukutheleleka kwe-Hp. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

 

Landelela

Isitatimende 31:31a:Ukuhlolwa okungahlaseli kuyanconywa ukuze kuqinisekiswe ukuthi i-Hp iyaqedwa yini ezigulini ezinezilonda ze-duodenal.

                    31b:Ngokuvamile, emavikini angu-8 kuya kwangu-12, i-gastroscopy inconywa ezigulini ezinezilonda zesisu ukuze zibhale ukuphulukiswa okuphelele kwesilonda. Ngaphezu kwalokho, lapho isilonda singapholi, i-biopsy ye-gastric mucosa inconywa ukuze igweme ukuhlukumeza. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

Isitatimende 32:Umdlavuza wesisu wasekuqaleni kanye neziguli ezine-MALT lymphoma yesisu esinokutheleleka kwe-Hp kufanele ziqinisekise ukuthi i-Hp iqedwa ngempumelelo yini okungenani amasonto ama-4 ngemva kokwelashwa. Kunconywa i-endoscopy yokulandelela. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)


Isikhathi sokuthumela: Jun-25-2019