( I-ASEAN, i-Association of Southeast Asian Nations, neMalaysia, Indonesia, Thailand, Philippines, Singapore, Brunei, Vietnam, Laos, Myanmar kanye neCambodia, iyiphuzu eliyinhloko lombiko wokuvumelana kwe-Bangkok okhishwe ngonyaka odlule, noma ingase ihlinzekele Ukwelashwa kwe-Helicobacter pylori Eminye imibono.

Ukutheleleka nge-Helicobacter pylori (Hp) kuhlala kuvela, futhi ochwepheshe emkhakheni wokugaya bebelokhu becabanga ngesu lokwelapha elingcono kakhulu. Ukwelashwa kokutheleleka nge-Hp emazweni ase-ASEAN: Ingqungquthela Yesivumelwano Yase-Bangkok yahlanganisa ithimba lochwepheshe ababalulekile abavela esifundeni ukuze babuyekeze futhi bahlole izifo ze-Hp ngokwemibandela yomtholampilo, kanye nokuthuthukisa izitatimende zokuvumelana, izincomo, kanye nezincomo zokwelashwa komtholampilo kokutheleleka nge-Hp e-ASEAN. amazwe. I-ASEAN Consensus Conference ibihanjelwe ochwepheshe bamazwe ngamazwe abangama-34 abavela emazweni ayi-10 angamalungu e-ASEAN naseJapan, eTaiwan nase-United States.

Umhlangano ubugxile ezihlokweni ezine:

(I) i-epidemiology kanye nezixhumanisi zezifo;

(II) izindlela zokuxilonga;

(III) imibono yokwelashwa;

(IV) ukulandelela ngemva kokuqedwa.

Isitatimende sokuvumelana

Isitatimende 1:I-1a: Ukutheleleka kwe-Hp kwandisa ingozi yezimpawu ze-dyspeptic. (Izinga Lobufakazi: Phezulu; Izinga Elinconyiwe: N/A); I-1b: Zonke iziguli ezine-dyspepsia kufanele zihlolwe futhi zelashwe ukutheleleka kwe-Hp. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 2:Ngenxa yokuthi ukusetshenziswa kokutheleleka kwe-Hp kanye/noma izidakamizwa ezingezona ukuvuvukala (ama-NSAID) kuhlobene kakhulu nezilonda ze-peptic, ukwelashwa okuyinhloko kwezilonda ze-peptic ukuqeda i-Hp kanye/noma ukuyeka ukusetshenziswa kwama-NSAID. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 3:Izehlakalo ezisezingeni lobudala zomdlavuza wesisu emazweni ase-ASEAN zingu-3.0 kuye ku-23.7 ngeminyaka eyi-100,000 yabantu. Emazweni amaningi e-ASEAN, umdlavuza wesisu uhlala ungenye yezimbangela eziyishumi eziphezulu zokufa komdlavuza. I-Gastric mucosa-associated lymphoid tissue lymphoma (isisu se-MALT lymphoma) ayivamile kakhulu. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: N/A)

Isitatimende 4:Ukuqedwa kwe-Hp kunganciphisa ingozi yomdlavuza wesisu, futhi amalungu omndeni eziguli ezinomdlavuza wesisu kufanele ahlolwe futhi alashwe i-Hp. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 5:Iziguli ezine-MALT lymphoma esiswini kufanele ziqedwe ku-Hp. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile) 

Isitatimende 6:6a: Ngokusekelwe emthwalweni womphakathi walesi sifo, kubiza ukonga ukwenza ukuhlolwa komphakathi kwe-Hp ngokuhlolwa okungahlaseli ukuvimbela ukuqedwa komdlavuza wesisu. (Izinga lobufakazi: liphezulu; izinga elinconyiwe: libuthakathaka)

6b: Okwamanje, emazweni amaningi e-ASEAN, ukuhlolelwa umdlavuza womphakathi wesisu nge-endoscopy akwenzeki. (Izinga Lobufakazi: Maphakathi; Izinga Elinconyiwe: Ebuthakathaka)

Isitatimende 7:Emazweni ase-ASEAN, imiphumela ehlukene yokutheleleka nge-Hp inqunywa ukusebenzisana phakathi kwezinto ze-Hp virulence, izici zokusingatha kanye nemvelo. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: N/A)

Isitatimende 8:Zonke iziguli ezinezilonda eziyingozi zomdlavuza wesisu kufanele zitholwe futhi zelashwe i-Hp, futhi zihlukanise ubungozi bomdlavuza wesisu. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

Indlela yokuxilongwa kwe-Hp

Isitatimende 9:Izindlela zokuxilonga ze-Hp esifundeni sase-ASEAN zifaka: ukuhlolwa kokuphefumula kwe-urea, ukuhlolwa kwe-fecal antigen (i-monoclonal) kanye nokuhlolwa kwe-urease okusheshayo okuqinisekisiwe (RUT)/histology. Ukukhetha indlela yokuthola kuncike kulokho isiguli esikuthandayo, ukutholakala, kanye nezindleko. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile) 

Isitatimende 10:Ukutholwa kwe-Hp okusekelwe ku-biopsy kufanele kwenziwe ezigulini ezithatha i-gastroscopy. (Izinga Lobufakazi: Maphakathi; Izinga Elinconyiwe: Liqinile)

Isitatimende 11:Ukutholwa kwe-Hp proton pump inhibitor (PPI) kuyekwa okungenani amaviki ama-2; ama-antibiotic ayekwa okungenani amaviki ama-4. (Izinga lobufakazi: liphezulu; isilinganiso esinconyiwe: siqinile)

Isitatimende 12:Uma kudingeka ukwelashwa kwe-PPI yesikhathi eside, kunconywa ukuthi kutholwe i-Hp ezigulini ezine-gastroesophageal reflux disease (GERD). (Izinga Lobufakazi: Maphakathi; Isilinganiso Esinconyiwe: Siqinile)

Isitatimende 13:Iziguli ezidinga ukwelashwa isikhathi eside ngama-NSAID kufanele zihlolwe futhi zelashwe i-Hp. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile) 

Isitatimende 14:Ezigulini ezinokopha kwe-peptic ulcer kanye ne-negative Hp biopsy, ukutheleleka kufanele kuqinisekiswe kabusha ngokuhlolwa kwe-Hp okwalandela. (Izinga Lobufakazi: Maphakathi; Izinga Elinconyiwe: Liqinile)

Isitatimende 15:Ukuhlolwa kokuphefumula kwe-urea kuyisinqumo esingcono kakhulu ngemva kokuqedwa kwe-Hp, futhi ukuhlolwa kwe-fecal antigen kungasetshenziswa njengenye indlela. Ukuhlolwa kufanele kwenziwe okungenani amaviki angu-4 ngemva kokuphela kokwelashwa kokuqeda. Uma kusetshenziswa i-gastroscope, i-biopsy ingenziwa. (Izinga lobufakazi: eliphezulu; izinga elinconyiwe: eliqinile)

Isitatimende 16:Kunconywa ukuthi iziphathimandla zezempilo zikazwelonke emazweni ase-ASEAN zibuyisele i-Hp ngokuhlolwa kokuxilonga nokwelashwa. (Izinga lobufakazi: liphansi; izinga elinconyiwe: eliqinile)