Ngesikhathi sokuhlolwa kwezokwelapha, ezinye izivivinyo zangasese nezibonakala ziyinkinga zivame ukweqiwa, njengokuhlolwa kwegazi elingabonakali lendle(FOBT).

Abantu abaningi, lapho bebhekene nesitsha kanye nenduku yokuthatha isampula yokuqoqa indle, bavame ukuyigwema ngenxa “yokwesaba ukungcola,” “amahloni,” noma “ukucabanga ukuthi kuwukusabela ngokweqile.” Kodwa-ke, lokhu “kuhlolwa kwendle” okuvame ukudelelwa kungaba ngumsindisi wempilo ezikhathini ezibucayi.

UNksz Wu, oneminyaka engu-59 ubudala, uvakashele umtholampilo ngemuva kokuchitha isonto lonke ephethe indle enegazi. Wayengalindele ukuthi ukuhlolwa ayekweqe iminyaka emithathu ilandelana, okokuqala, kuzobonisa ukuthi unegciwane ngendlela ye-immunochemical, okuholele ekuxilongweni kokuqala komdlavuza we-rectal nge-colonoscopy. Ngemva kokususwa ngokuhlinzwa, izinga lakhe lokusinda iminyaka emihlanu lidlule ku-90%.

Ngokuphambene nalokho, umakhelwane wakhe, uMnu. Zhang, owayeseyishaye indiva le "ndlela enzima" efomini lakhe lokuhlolwa kwezokwelapha, watholakala enomdlavuza we-colorectal osezingeni eliphezulu kuphela ngemuva kokuzwa ubuhlungu besisu kanye nendle enegazi, okwehlisa izinga lokusinda kwakhe libe ngaphansi kuka-10%.

Kungani kungafanele weqeukuhlolwa kwegazi elingabonakali lendle?
Inani eliyinhloko leI-FOBTkulele ekutholeni (ukuphuma kwegazi okuncane) endleleni yokugaya ukudla. Uma kukhona ukopha okuncane (nsuku zonke okungu-2-5ml kuphela), amangqamuzana abomvu egazi asuke esegayiwe futhi ephukile, okwenza indle ibonakale ijwayelekile ngaphandle kwegazi elibonakalayo futhi ingatholakali ngaphansi kwe-microscope. Kodwa-ke, ukubhujiswa kwamangqamuzana abomvu egazi kukhipha i-hemoglobin, engatholakala ngezindlela zamakhemikhali noma ze-immunochemical.

Lokhu kopha okuncane kungaba uphawu lokuqala lwezimila zomgudu wokugaya ukudla (njengomdlavuza we-colorectal noma wesisu). Izifundo zithole ukuthi ama-87% eziguli ezinezimila zomgudu wokugaya ukudla zinokuhlolwa kwegazi okubonakalayo kwendle. Njengoba ukopha kwesimila kwenzeka ngezikhathi ezithile, ukuhlolwa okukodwa kungase kuphuthelwe ukuxilongwa. Kodwa-ke, ukuhlolwa okuvamile kwaminyaka yonke kungathuthukisa kakhulu izinga lokutholakala kwezilonda. Ngokwezibalo ezingaphelele, ukuhlolwa kwe-FOBT okuqhubekayo kunganciphisa ukufa komdlavuza we-colorectal ngo-10%-30%. Njengamanje, iziqondiso eziningi zokuvimbela zincoma kakhulu njengento yokuhlola.

Ukuhlolwa Okuhlanganisiwe Kuthuthukisa Ukunemba

Ucwaningo lubonisa ukuthi ukuhlolwa kwe-hemoglobin (Hb) kanye i-transferrin (Tf)ingahlanganisa izimo eziningi zokopha futhi ithuthukise ukunemba kokutholwa.

I-TransferrinKuzinzile kakhulu endle kune-hemoglobin, ngakho-ke ukuhlolwa kokubili kunganciphisa ama-negative angamanga abangelwa ukunyamalala kwe-hemoglobin antigenicity. Ukuhlolwa okuhlanganisiwe kunikeza izinzuzo ezilandelayo: ukucaca okuqinile, ukuzwela okuphezulu, ukusebenza okulula, ukuqedwa kwesinyathelo esisodwa, kanye nokuchazwa kwemiphumela okulula.

Ubani Okufanele Abhekane Nalolu Hlelo Lokuhlolwa?

Abantu abaneminyaka engu-40 nangaphezulu kufanele bahlolwe igazi elingcolile okungenani kanye ngonyaka.

Uma unesinye sezimo ezilandelayo, kufanele wandise imvamisa yokuhlolwa kwegazi elingabonakali lendle:

A. Umlando womndeni womdlavuza wesisu noma we-colorectal.

B. Umlando womdlavuza we-colorectal, i-colorectal adenoma, noma i-post-polypectomy.

C. Umlando we-colitis.

D. Umlando wezimila ezibangela umdlavuza kwabesifazane ngokwelashwa ngemisebe ye-pelvic.

E. Iminyaka engaphezu kweyi-10 ngemva kokususwa kwe-cholecyst.

F. I-anemia eyingozi ephindaphindayo.

G. I-gastritis engapheli engalawuleki, izilonda zesisu, ama-polyp esiswini, noma umlando wokuhlinzwa kwesisu.

H. Abesilisa abakhuluphele ngokweqile ngamakhilogremu angu-20-25 noma ababhemayo.

I. Ukutheleleka kwe-Helicobacter pylori: kwandisa ingozi yomdlavuza wesisu ngokuphindwe kabili kuya kathathu.

Isiphetho esivela ku-Xiamen Baysen Medical

Thina i-baysene Medical sinayoI-FOB Ikhithi yokuhlolafuthiIkhithi yokuhlola i-TransferrinLapha sihlala sigxila emakhonweni okuxilonga ukuze sithuthukise ikhwalithi yokuphila.