I-Cal iyi-heterodimer, eyakhiwa yi-MRP 8 kanye ne-MRP 14. Itholakala kuma-neutrophils cytoplasm futhi itholakala kuma-membranes eseli le-mononuclear. I-Cal iyi-acute phase proteins, ine-acute phase ezinzile cishe isonto elilodwa endle yabantu, itholakala njengophawu lwesifo samathumbu esivuvukalayo. Ikhithi iyisivivinyo esilula, esibonakalayo se-semiqualitative esithola i-cal endle yabantu, inokuzwela okuphezulu kokuthola kanye nokucaciswa okuqinile. Isivivinyo esisekelwe ku-high specificit double antibodies sandwich reaction principle kanye ne-gold immunochromatographic assay analysis techniques, singanikeza umphumela zingakapheli imizuzu eyi-15.