I-Cal iyi-heterodimer, eyakhiwe nge-MRP 8 kanye ne-MRP 14. Itholakala kuma-neutrophils cytoplasm futhi evezwa kuma-mononuclear cell membranes. I-Cal iyi-acute phase proteins, inesigaba esizinzile cishe isonto elilodwa endle yomuntu, kunqunywa ukuthi ibe umaka wesifo samathumbu okuvuvukala. Ikhithi iwukuhlola okulula, okubukwayo kwe-semiqualitative okuthola i-cal endle yomuntu, inokuzwela okuphezulu kokutholwa kanye nokucaciswa okuqinile. Ukuhlolwa okusekelwe kumgomo wokusabela wesangweji wama-antibodies aphindwe kabili kanye nobuchwepheshe bokuhlaziya i-immunochromatographic assay, kunganikeza umphumela phakathi nemizuzu eyi-15.