Ukuhlolwa kwe-Prostate Specific Antigen PSA okuzwela kakhulu
UKUSETSHENZISWA OKUHLOSIWE
Ikhithi yokuxilongaye-Prostate Specific Antigen (i-fluorescence immunochromatographic assay) i-fluorescence immunochromatographic
isivivinyo sokutholwa komthamo we-Prostate Specific Antigen (PSA) ku-serum yomuntu noma i-plasma, esetshenziselwa kakhulu ukuxilonga isifo se-prostatic. Wonke amasampula amahle kufanele aqinisekiswe ngezinye izindlela. Lokhu kuhlola kuhloselwe
ukusetshenziswa kochwepheshe bezempilo kuphela.
ISIFINYEZO
I-PSA (I-Prostate Specific Antigen) ihlanganiswa futhi ikhishwe amaseli e-prostate epithelial ibe isidoda futhi ingenye yezingxenye eziyinhloko ze-seminal plasma. Iqukethe izinsalela ze-amino acid ezingu-237 kanye nesisindo sayo samangqamuzana cishe ama-34kD. Inomsebenzi we-serine protease weketango elilodwa glycoprotein, iqhaza enqubweni ye-liquefaction yesidoda. I-PSA egazini iyisamba se-PSA ekhona kanye ne-PSA ehlanganisiwe. amazinga e-plasma yegazi, ku-4 ng/mL ngenani elibalulekile, i-PSA kumdlavuza wendlala yesinye Ⅰ ~ Ⅳ isikhathi sokuzwela esingu-63%, 71%, 81% no-88% ngokulandelanayo.