Ikhithi yokuxilonga ye-prostate ethize yamahhala ye-Antigen
UKUSETSHENZISWA OKUHLOSIWE
Ikhithi yokuxilonga yamahhala ye-Prostate Specific Antigen (i-fluorescence immunochromatographic assay) isivivinyo se-fluorescence immunochromatographic sokutholwa komthamo we-Prostate Specific Antigen (fPSA) yamahhala ku-serum yomuntu noma i-plasma. Isilinganiso se-fPSA/tPSA singasetshenziswa ekuxilongeni okuhlukile komdlavuza wendlala yesinye kanye ne-benign prostatic hyperplasia. Wonke amasampula amahle kufanele aqinisekiswe ngezinye izindlela. Lokhu kuhlolwa kuhloselwe ukusetshenziswa ngochwepheshe bezempilo kuphela.
ISIFINYEZO
I-prostate-specific antigen (fPSA) yamahhala i-prostate-specific antigen ekhishelwa egazini ngendlela yamahhala futhi ikhishwa amaseli e-prostate epithelial. I-PSA (I-Prostate Specific Antigen) ihlanganiswa futhi ikhishwe amaseli e-prostate epithelial ibe isidoda futhi ingenye yezingxenye eziyinhloko ze-seminal plasma. Iqukethe izinsalela ze-amino acid ezingu-237 kanye nesisindo sayo samangqamuzana cishe ama-34kD. Inomsebenzi we-serine protease weketango elilodwa glycoprotein, iqhaza enqubweni ye-liquefaction yesidoda. I-PSA egazini iyisamba se-PSA yamahhala kanye ne-PSA ehlanganisiwe. amazinga e-plasma yegazi, ku-4 ng/mL ngenani elibalulekile, i-PSA kumdlavuza wendlala yesinye Ⅰ ~ Ⅳ isikhathi sokuzwela esingu-63%, 71%, 81% no-88% ngokulandelana.