Unyango losulelo lweHp
Inkcazo 17:Umyinge wezinga lokunyanga iiprothokholi zodidi lokuqala kwiintlobo ezinovakalelo kufuneka ubuncinane zibe yi-95% yezigulane ezinyangwayo ngokohlalutyo lwe-protocol set analysis (PP), kunye nohlalutyo lonyango lwangabom (ITT) lufanele lube yi-90% okanye ngaphezulu. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: elomeleleyo)
Inkcazo 18:I-Amoxicillin kunye ne-tetracycline ziphantsi kwaye zizinzile. Uxhathiso lweMetronidazole luphezulu kakhulu kumazwe ase-ASEAN. Ukuxhathisa kwe-clarithromycin kuye kwanda kwiindawo ezininzi kwaye kunciphise izinga lokuphelisa unyango oluqhelekileyo oluphindwe kathathu. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: N/A)
Inkcazo 19:Xa izinga lokumelana ne-clarithromycin li-10% ukuya kwi-15%, libhekwa njengesantya esiphezulu sokumelana, kwaye ummandla uhlukaniswe kwindawo ephezulu yokuchasana kunye nommandla ophantsi. (Inqanaba loBungqina: Phakathi; Inqanaba elicetyiswayo: N/A)
Inkcazo 20:Kunyango oluninzi, ikhosi ye-14d ilungile kwaye kufuneka isetyenziswe. Ikhosi emfutshane yonyango inokwamkelwa kuphela ukuba ibonakaliswe ngokuthembekileyo ukufikelela kwi-95% yezinga lokunyanga nge-PP okanye i-90% yezinga lokunyanga ngokuhlalutya kwe-ITT. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: elomeleleyo)
Inkcazo 21:Ukhetho lonyango olucetyiswayo lonyango lokuqala luyohluka ngokwengingqi, indawo, kunye neepateni zokuxhathisa amayeza okubulala iintsholongwane ezaziwa okanye ezilindelwe zizigulane ezizimeleyo. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: elomeleleyo)
Inkcazo 22:Irejimeni yonyango lodidi lwesibini kufuneka ibandakanye amayeza okubulala iintsholongwane angazange asetyenziswe ngaphambili, afana ne-amoxicillin, i-tetracycline, okanye amayeza okubulala iintsholongwane angazange anyuswe ukuxhathisa. (Inqanaba lobungqina: liphezulu; inqanaba elicetyiswayo: elomeleleyo)
Inkcazo 23:Esona sibonakaliso siphambili sovavanyo lokuchaphazeleka kwechiza lokubulala iintsholongwane kukwenza unyango olusekwe kubuntununtunu, olwenziwa ngoku emva kokusilela kunyango lodidi lwesibini. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Inkcazo 24:Apho kunokwenzeka, unyango lolungiso kufuneka lusekelwe kuvavanyo lovakalelo. Ukuba ngaba uvavanyo lokuba sesichengeni alunakwenzeka, amachiza anoxhathiso lwamachiza akufuneki aqukwe, kwaye amachiza anoxhathiso oluphantsi kumachiza kufuneka asetyenziswe. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Inkcazo 25:Indlela yokunyusa izinga lokuphelisa i-Hp ngokunyusa umphumo we-antisecretory we-PPI idinga i-CYP2C19 genotype esekelwe kwi-host, mhlawumbi ngokunyusa umthamo ophezulu we-PPI we-metabolic okanye ngokusebenzisa i-PPI engaphantsi kwe-CYP2C19. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Inkcazo 26:Xa kukho ukunganyangeki kwe-metronidazole, ukwandisa umthamo we-metronidazole ukuya kwi-1500 mg/d okanye ngaphezulu kunye nokwandisa ixesha lonyango ukuya kwiintsuku ezili-14 kuya kwandisa isantya sonyango lwe-quadruple therapy nge-expectorant. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Inkcazo 27:Iiprobiotics zinokusetyenziswa njengonyango lokuncedisa ukunciphisa ukusabela okubi kunye nokuphucula ukunyamezela. Ukusetyenziswa kweeprobiotics kunye nonyango oluqhelekileyo kunokubangela ukonyuka okufanelekileyo kumazinga okuphelisa. Nangona kunjalo, ezi zibonelelo azikhange ziboniswe njengeendleko ezifanelekileyo. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: buthathaka)
Inkcazo 28:Isisombululo esiqhelekileyo kwizigulane ezingadibaniyo nepenicillin kukusetyenziswa konyango olune-expectorant. Olunye ukhetho luxhomekeke kwipatheni yokuchaphazeleka kwendawo. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Inkcazo 29:Umlinganiselo wonyaka wokuphinda uhlaziywe yi-Hp echazwe ngamazwe ase-ASEAN yi-0-6.4%. (Inqanaba lobungqina: phakathi)
Inkcazo 30:I-dyspepsia enxulumene ne-Hp iyachongeka. Kwizigulane ezine-dyspepsia ezinosulelo lwe-Hp, ukuba iimpawu ze-dyspepsia zikhululeka emva kokuba i-Hp isuswe ngempumelelo, ezi mpawu zinokuthi zibangelwa usulelo lwe-Hp. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Ukulandelisa
Ingxelo 31:31aUviwo olungathinteliyo luyacetyiswa ukuba kuqinisekiswe ukuba i-Hp iyacinywa kwizigulane ezinezilonda ze-duodenal.
31b:Ngokuqhelekileyo, kwiiveki ezisi-8 ukuya kwezi-12, i-gastroscopy inconywa kwizigulane ezinezilonda zesisu ukurekhoda ukuphiliswa okupheleleyo kwesilonda. Ukongezelela, xa isilonda singaphili, i-biopsy ye-gastric mucosa inconywa ukuba ikhuphe ububi. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Inkcazo 32:Umhlaza wesisu sokuqala kunye nezigulane ezine-MALT lymphoma yesisu esinesifo se-Hp kufuneka siqinisekise ukuba i-Hp ichithwa ngempumelelo ubuncinane kwiiveki ze-4 emva kwonyango. I-endoscopy yokulandelela iyacetyiswa. (Inqanaba lobungqina: liphezulu; ukukala okucetyiswayo: okunamandla)
Ixesha lokuposa: Jun-25-2019