I-Severe acute Respiratory Syndrome i-coronavirus 2 (SARS-CoV-2), eyona pathogen yesifo se-coronavirus samva nje sika-2019 (COVID-19) bhubhane, sisifo sentsholongwane ye-RNA enemisonto enye enobukhulu obungama-30 kb. . Iintlobo ezininzi ze-SARS-CoV-2 ezinotyikityo olwahlukileyo oluguqukileyo ziye zavela kulo lonke ubhubhane. Ngokuxhomekeke kumhlaba weprotein eguqukayo, ezinye izinto ezahlukeneyo zibonise ukugqithisela okuphezulu, ukosuleleka, kunye nentsholongwane.

Umnombo we-BA.2.86 we-SARS-CoV-2, owaqatshelwa okokuqala ngo-Agasti 2023, wohluke ngokwephylogenetically kwimida ye-Omicron XBB ejikelezayo ngoku, kubandakanywa i-EG.5.1 kunye ne-HK.3. Umnombo we-BA.2.86 uqulethe ngaphezulu kwe-30 yeenguqu kwi-protein ye-spike, ebonisa ukuba lo mgca unakho kakhulu ukuphepha ukugonywa kwangaphambili kwe-anti-SARS-CoV-2.

I-JN.1 (BA.2.86.1.1) lolona tshintsho lusanda kuvela lwe-SARS-CoV-2 oluphuma kumnombo we-BA.2.86. I-JN.1 iqulethe i-hallmark ukuguqulwa kwe-L455S kwi-protein ye-spike kunye nezinye iinguqu ezintathu kwiiprotheni ezingenayo i-spike. Uphononongo oluphanda i-HK.3 kunye nezinye iinguqu ze-"FLip" zibonise ukuba ukufumana i-L455F ukuguqulwa kwiprotheni ye-spike inxulumene nokunyuka kwentsholongwane yentsholongwane kunye nokukwazi ukuphepha komzimba. Iinguqu ze-L455F kunye ne-F456L zibizwa ngokuba "Phenya”utshintsho ngenxa yokuba batshintsha iindawo ezimbini ze-amino acid, ezibhalwe F kunye no-L, kwiprotheni ye-spike.

I-Baysen Medical inokubonelela ngovavanyo lwe-covid-19 ukuze uyisebenzise ekhaya, wamkelekile ukuba uqhagamshelane nathi ngeenkcukacha ezithe vetshe.