Yintoni i-β-subunit yasimahla yechorionic gonadotropin yomntu?
I-β-subunit yasimahla yenye i-glycosylated monomeric variant ye-hCG eyenziwe zizo zonke izifo eziphucukileyo ezingezizo ze-trophoblastic. I-β-subunit yasimahla ikhuthaza ukukhula kunye nobubi bomhlaza ophambili. Uhlobo lwesine lwe-hCG yi-pituitary hCG, eveliswa ngexesha lokuya esikhathini kwabasetyhini.
Yintoni injongo yokuyisebenzisa simahlaI-β-subunit yekhithi ye-chorionic gonadotropin yomntu yokuvavanya ngokukhawuleza?
Le khithi iyasebenza kwi-vitro quantitative ubhaqo lwe-β-subunit yasimahla ye-chorionic gonadotropin (F-βHCG) kwisampulu ye-serum yabantu, efanelekile kuvavanyo oluncedisayo lomngcipheko wokuba abafazi baphathe umntwana nge-trisomy 21 (Down syndrome) kwiinyanga ezi-3 zokuqala zokukhulelwa. Le khithi ibonelela kuphela i-β-subunit yasimahla yeziphumo zovavanyo lwe-chorionic gonadotropin yabantu, kwaye iziphumo ezifunyenweyo ziya kusetyenziswa ngokudityaniswa nolunye ulwazi lwezonyango ukuze kuhlalutywe. Kufuneka isetyenziswe kuphela ngabasebenzi bezempilo