I-Fecal Calprotectin (FC) yi-Calcium eyi-36.5 kda ye-Calcium ebopha i-60% ye-neutrophil cytoplasmic cytoplasmic kwaye iqokelelwe kwaye ivunyelwe kwiindawo zokuvuvukala kwamathumbu kwaye ikhutshiwe kwi-feeds.

I-FC inezinto ezahlukeneyo zebhayoloji, kubandakanya ne-antibacterial, kugonyotoritory, kunye nezinto eziphilayo. Ngokukodwa, ubukho be-FC bunxulumene nemveliso yokufuduka kwe-neutrophils kwiphecana le-gestrointenal. Ke ngoko, luphawu oluluncedo lwesuntswana lwamathumbu okuchonga ubukho kunye nobungakanani bokuvuvukala emathunjini.

Inokuthatha nje amanyathelo amane okuphuhlisa ukuvela kwamathumbu kuMhlaza: U-Idorstinal Ukuvuvukala -> I-polylinal polyps -> i-Adenoma -> umhlaza onomhlaza we-adenoma. Le nkqubo ithatha iminyaka okanye amashumi eminyaka, ibonelela ngamathuba okwaneleyo ekuhlolweni kwangoko kwezifo zamathumbu. Nangona kunjalo, kuba abantu abaninzi benganikeli ingqalelo ekuhlolweni kwangoko, iimeko ezininzi zomhlaza weqhekeza zifunyaniswa kwinqanaba eliphezulu.

Ngokwedatha egunyazisiweyo ekhaya nakwamanye amazwe, inqanaba leminyaka emi-5 yokusinda kunyaka wenqanaba lokuqala lwe-colorecy calrear linokufikelela kwi-90% ukuya kwi-95%. Ukuba yi-carcinoma kwi-5 Inqanaba leminyaka emi-5 yokusinda kwenqanaba lokugqibela le-colorecrel iphantsi kwe-10%. Ezi datha zicebisa ukuba uvavanyo lwangoko lubalulekile ekuphuculeni ukusinda kunye nokunyanga amaxabiso ezigulana ngomhlaza weqhekeza. Okwangoku, ezinye iingcali zicebise ukuba abantu abaqhelekileyo bafanele bahlolwe kwangoko umhlaza omhlaza emva kweminyaka engama-40, nabantu abanembali yosapho okanye ezinye izinto zomngcipheko omkhulu kufuneka zihlolwe kwangoko.

Ukufunyanwa kwe-Calprotectin yokufumanisa ukuqashaNgaba imveliso engenabuhlungu, engahlaseli, enokusebenzisana enokusetyenziswa ekudaleni inqanaba lokuvuvukala kwamathumbu kunye nokuncedisa ekufumaneni izifo ezinxulumene ne-inforation (i-FORMMAIGE, i-adefoma, umhlaza wama-Adenoma. Ukuba uvavanyo lwezolompikisi alunanto, akufuneki wenze i-colonoscopy yexesha. Ukuba iziphumo zovavanyo zilungile, musa ukothuka kakhulu. Uninzi lweziphumo zeposi-colonoscopy zizilonda zokhuseleko ezinjengee-adherons. Ezi zilonda zinokulawulwa ngokukuko ngokufumana ungenelelo kwangoko.