I-Cal i-heterodimer, ehlanganiswe ne-MRP 8 kunye ne-MRP 14. Ikhona kwi-neutrophils cytoplasm kwaye ibonakaliswe kwi-mononuclear cell membranes. I-Cal i-acute phase proteins, inesigaba esizinzile kakuhle malunga neveki enye kwilindle lomntu, izimisele ukuba ibe yinto ephawulekayo yesifo sesibindi. Ikhithi luvavanyo olulula, olubonakalayo lwe-semiqualitative olufumanisa i-cal kwilindle lomntu, inovakalelo oluphezulu lokubona kunye neenkcukacha ezinamandla. Uvavanyo olusekwe kumgaqo-nkqubo wokuphendula wesangweji ye-antibodies ephindwe kabini kunye negolide ye-immunochromatographic assay, inokunika iziphumo kwimizuzu eli-15.