I-C-Peptide (i-C-Peptide) i-peptide edibanisayo eyenziwe nge-31 amino acids kunye nobunzima be-molecular malunga ne-3021 Daltons. Ipancreatic β-cells yepancreas yenza iproinsulin, eyityathanga leprotein elide kakhulu. I-proinsulin idilizwe ibe ngamacandelo amathathu phantsi kwesenzo se-enzymes, kwaye amacandelo angaphambili nangemuva aphinde adityaniswe ukuze abe yi-insulin, ehlanganiswe ne-A kunye ne-B chain, ngelixa icandelo eliphakathi lizimele kwaye liyaziwa ngokuba yi-C-peptide. . I-insulin kunye ne-C-peptide zikhutshelwa ngokulinganayo, kwaye emva kokungena egazini, uninzi lwe-insulin luyenziwa lungasebenzi sisibindi, ngelixa i-C-peptide ingafane ithathwe sisibindi, kunye nokuwohloka kwe-C-peptide kuhamba kade kune-insulin. Ukuxinwa kwe-C-peptide egazini kuphezulu kune-insulin, ngokuqhelekileyo ngaphezu kwamaxesha e-5, ngoko ke i-C-peptide ibonisa ngokuchanekileyo umsebenzi we-pancreatic islet. β-iiseli. Umlinganiselo wezinga le-C-peptide ungasetyenziselwa ukuhlelwa kwesifo sikashukela kunye nokuqonda umsebenzi we-pancreatic β-cell of diabetes mellitus. Umlinganiselo wenqanaba le-C-peptide ungasetyenziselwa ukwahlula isifo sikashukela kunye nokuqonda umsebenzi we-pancreatic β-cell kwizigulane ezinesifo sikashukela. Okwangoku, iindlela zokulinganisa i-C-peptide ezisetyenziswa ngokubanzi kwiiklinikhi zonyango ziquka i-radioimmunoassay, i-enzyme immunoassay, i-electrochemiluminescence, i-chemiluminescence.