Pepsinogen Ie entsoe le ho patoa ke lisele tse ka sehloohong tsa sebaka sa oxyntic glandular ka mpeng, 'me pepsinogen II e entsoe le ho patoa ke sebaka sa pyloric sa mpa. Ka bobeli li kentsoe tšebetsong ho li-pepsins ka har'a lumen ea ka mpeng ke HCl e hlahisoang ke li-fundic parietal cell.

1.Pepsinogen II ke eng?
Pepsinogen II ke e 'ngoe ea liprotheine tse' nè tsa aspartic: PG I, PG II, Cathepsin E le D. Pepsinogen II e hlahisoa haholo-holo ho Oxyntic gland mucosa ea mpa, gastric antrum le duodenum. E hlahisoa haholo-holo ka har'a lumen ea gastric le ho potoloha.
2.Likaroloana tsa pepsinogen ke life?
Pepsinogens e na le ketane e le 'ngoe ea polypeptide e nang le boima ba molek'hule e ka bang 42,000 Da. Li-pepsinogens li entsoe le ho patoa haholo-holo ke lisele tse ka sehloohong tsa mpa ea mpa ea motho pele li fetoloa ho proteolytic enzyme pepsin, e leng ea bohlokoa bakeng sa ts'ebetso ea tšilo ea lijo ka mpeng.
3.Phapano ke efe lipakeng tsa pepsin le pepsinogen?
Pepsin ke enzyme ea ka mpeng e sebeletsang ho sila liprotheine tse fumanoang lijong tse jeoang. Lisele tse ka sehloohong tsa ka mpeng li hlahisa pepsin joalo ka zymogen e sa sebetseng e bitsoang pepsinogen. Lisele tsa parietal ka har'a lesela la mpa li hlahisa hydrochloric acid e theolang pH ea mpa.

Setsi sa Tlhahlobo bakeng sa Pepsinogen I/ PepsinogenII (Fluorescence Immuno Assay)ke fluorescence immunochromatographic assay bakeng sa phumano ea bongata ba PGI/PGII serum ea motho kapa plasma, E sebelisoa haholo ho lekola tšebetso ea lisele tsa gastric oxyntic tšoelesa le lefu la gastric fundus mucinous kliniking.

Rea u amohela ho ikopanya le lintlha tse ling.