Severe acute breathing syndrome coronavirus 2 (SARS-CoV-2), pathogen e bakang lefu la seoa la morao-rao la 2019 (COVID-19), ke kokoana-hloko ea RNA e nang le thipa e le 'ngoe e boholo ba genome e ka bang 30 kb. . Mefuta e mengata ea SARS-CoV-2 e nang le li-signature tse fapaneng tse fetotsoeng e hlahile ho pholletsa le seoa sena. Ho ipapisitse le sebopeho sa bona sa phetoho ea protheine ea spike, mefuta e meng e bonts'itse phetisetso e phahameng, ts'oaetso le ts'oaetso.

Leloko la BA.2.86 la SARS-CoV-2, le ileng la hlwauwa la pele ka Phato 2023, le fapane ka tsela ya phylogenetic le leloko le ntseng le potoloha la Omicron XBB, ho kenyeletswa EG.5.1 le HK.3. Leloko la BA.2.86 le na le liphetoho tse fetang 30 ka har'a protheine ea spike, e bontšang hore leloko lena le khona haholo ho qoba ho itšireletsa khahlanong le SARS-CoV-2 e neng e le teng pele.

JN.1 (BA.2.86.1.1) ke mofuta o sa tsoa hlaha oa SARS-CoV-2 o tsoang lelokong la BA.2.86. JN.1 e na le phetoho e ikhethang L455S ho protheine ea spike le liphetoho tse ling tse tharo ho liprotheine tse se nang spike. Liphuputso tse batlisisang HK.3 le mefuta e meng ea "FLip" li bontšitse hore ho fumana phetoho ea L455F ho protheine ea spike ho amahanngoa le ho eketseha ha tšoaetso ea kokoana-hloko le matla a ho qoba ho itšireletsa mafung. Liphetoho tsa L455F le F456L li reheletsoe "Flip”Liphetoho hobane li fetola maemo a li-amino acid tse peli, tse ngotsoeng F le L, protheine ea spike.

We baysen medical e ka fana ka tlhahlobo ea covid-19 bakeng sa ts'ebeliso ea lapeng, rea u amohela ho ikopanya le rona bakeng sa lintlha tse ling.