Pepsinogen Iwaxaa lagu farsameeyaa oo ay siidaayaan unugyada madaxa ee gobolka qanjirada oksijiinta ee caloosha, iyo pepsinogen II waxaa lagu farsameeyaa oo lagu qariyaa gobolka pyloric ee caloosha. Labaduba waxa lagu hawlgeliyay pepsins ee lumen gastric HCl oo ay siiyeen unugyo fundic parietal unugyo ah.

1.Waa maxay pepsinogen II?
Pepsinogen II waa mid ka mid ah afar borotiinka aspartic: PG I, PG II, Cathepsin E iyo D. Pepsinogen II waxaa lagu soo saaraa ugu horreyntii qanjidhada Oxyntic ee caloosha, antrum gastric iyo duodenum. Waxay inta badan ku darsataa lumen gastric iyo wareegga wareegga.
2.Waa maxay qaybaha pepsinogen?
Pepsinogens waxay ka kooban yihiin hal silsilad polypeptide ah oo miisaankeedu yahay 42,000 Da. Pepsinogens waxa la farsameeyay oo ay sirayaan ugu horrayn unugyada madaxa gastric ee caloosha bini'aadamka ka hor inta aan loo beddelin pepsin-ka borotiinka, kaas oo muhiim u ah hababka dheef-shiidka caloosha.
3.Waa maxay faraqa u dhexeeya pepsin iyo pepsinogen?
Pepsin waa enzyme caloosha oo u adeegta dheefshiidka borotiinnada laga helo cuntada la dhuuqay. Unugyada madaxa gastric waxay soo daayaan pepsin sida zymogen aan firfircoonayn oo loo yaqaan pepsinogen. Unugyada parietal ee ku jira xuubka caloosha ayaa soo daaya hydrochloric acid taasoo hoos u dhigta pH ee caloosha.

Qalabka ogaanshaha ee Pepsinogen I/ PepsinogenII ( Fluorescence Immuno Assay)waa qiimaynta immunochromatographic fluorescence ee lagu ogaanayo tirada PGI/PGII ee serum bini'aadamka ama balasmaha, Waxaa inta badan loo isticmaalaa in lagu qiimeeyo shaqada unugyada qanjidhada oksintic ee qanjidhada gastric fundus mucinous qanjidhada qanjidhada ee kiliinikada.

Ku soo dhawoow la xidhiidh wixii faahfaahin dheeraad ah