Interleukin-6 i polypeptide ine maviri glycoprotein cheni, ine molecular huremu hwe130kd. Senhengo yakakosha ye cytokine network, interleukin-6 (IL-6) inobata basa repakati mukuitika kwekuzvimba, uye inogona kuyananidza acute phase reaction yechiropa, uye inokurudzira kugadzirwa kweC-reactive protein (CRP) uye fibrinogen. Zvirwere zvakawanda zvinotapukira zvinogona kukonzera kukwira kweserum IL-6 level, uye IL-6 nhanho yakabatana zvakanyanya nemhedzisiro yemurwere. Se pleiotropic cytokine ine mabasa akawandisa, IL-6 inovanzwa neT cell, B cell, mononuclear phagocyte, uye endothelial cell, uye chikamu chakakosha cheanopisa mediator network. Pakaitika kuzvimba kuita, IL-6's yakatanga kuburitswa, iyo inokurudzira kugadzirwa kweCRP uye procalcitonin (PCT) pakugadzirwa kwayo. Ichagadzirwa nekukurumidza kana paine hutachiona, kukuvara kwemukati nekunze, kuvhiyiwa, kushushikana kwekuita, kufa kwehuropi, tumorigenesis, uye acute inflammatory reaction process yemamwe mamiriro. IL-6 inobatanidzwa mukuitika uye kukura kwezvirwere zvakawanda, chiyero cheropa rayo chakanyatsobatanidzwa nekuputika, hutachiona hwehutachiona uye chirwere che autoimmune, uye kuchinja kwayo kunoitika kare kupfuura CRP. Maererano nemigumisiro yekutsvakurudza, IL-6 level inowedzera nokukurumidza pahutachiona hwehutachiona, PCT level inowedzera mushure me2h, asi CRP inongowedzera nokukurumidza mushure me6h. Kuvharidzirwa kusina kujairika kana gene kutaura kweIL-6 kazhinji kunogona kukonzera kuitika kwezvirwere zvakatevedzana, huwandu hwakawanda hweIL-6 hunogona kuvanzwa mukutenderera kweropa muhutano hwehutano, uye kuonekwa kweIL-6 kunokosha zvikuru pakuongororwa kwechirwere uye kutonga kwekufungidzira.