AOTELEGA

I le avea ai o se porotini vaega ogaoga, o le serum amyloid A e aofia i polotini eseese o le aiga apolipoprotein, lea.
e iai le mamafa mole mole e tusa. 12000. Tele cytokines o loʻo aʻafia i le faʻatonutonuina o faʻamatalaga SAA
i le tali atu i vaega ogaoga. Fa'aosofia e le interleukin-1 (IL-1), interleukin-6 (IL-6) ma le tumor necrosis factor-α
(TNF-α), SAA o loʻo faʻapipiʻiina e macrophages faʻagaoioia ma fibroblast i le ate, lea e puupuu le afa o le ola e naʻo.
e tusa ma le 50 minute. SAA faʻatasi ma lipoprotein maualuga (HDL) i totonu o le toto vave pe a faʻapipiʻiina i le ate, lea
e manaʻomia le faʻaleagaina e le serum, cell surface ma intracellular protease. I le tulaga o se maʻi maʻi masani
fulafula poʻo faʻamaʻi, faʻaleagaina le fua o le SAA i totonu o le tino e manino lava le faʻagesegese aʻo faʻateleina le faʻasologa,
lea e taʻitaʻia ai le faʻaauau pea o le maualuga o le SAA i le toto. O le SAA o se porotini vaega ma'i ma fa'ama'i
faʻailoga faʻapipiʻiina e hepatocytes. Ole maualuga ole SAA ile toto ole a fa'atupula'ia ile lua itula
tupuga o le mumū, ma le SAA faʻatonuga o le a oʻo i le 1000-taimi faʻateleina i le taimi o le ogaoga
fulafula. O le mea lea, e mafai ona faʻaaogaina le SAA e fai ma faʻamaoniga o faʻamaʻi pipisi o microbial poʻo faʻamaʻi eseese, lea
e mafai ona faafaigofieina le suʻesuʻeina o le mumū ma le mataʻituina o gaioiga togafitiga.

O la matou Pusa Fa'ata'ita'iga mo le Serum Amyloid A (Fluorescence Immunochromatographic Assay) e fa'atatau ile su'esu'ega fa'afuainumera in vitro ole antibody ile serum amyloid A (SAA) ile sua o le tagata/plasma/toto atoa fa'ata'ita'iga, ma e fa'aaogaina mo su'esu'ega fesoasoani o le ma'i ma'i ma'i po'o. fa'ama'i.

Fa'afeiloa'i e fa'afeso'ota'i mo nisi fa'amatalaga pe a iai sou fiafia.


Taimi meli: Tes-28-2022