Pepsinogen I.ikomatanyirizwa hamwe kandi ikarekurwa ningirabuzimafatizo nkuru yakarere ka oxydeque glandular yo mu gifu, na pepsinogen II ikomatanyirizwa hamwe kandi ikarekurwa nakarere ka pyloric igifu. Byombi bikoreshwa kuri pepsine muri gastric lumen na HCl isohorwa na selile parietal selile.

1. Pepsinogen II ni iki?
Pepsinogen II ni imwe muri enye za poroteyine enye: PG I, PG II, Cathepsin E na D. Pepsinogen II ikorwa cyane cyane muri Oxyntic gland mucosa yo mu gifu, antrum gastric na duodenum. Isohoka cyane cyane mu gifu no mu kuzenguruka.
2.Ni ibihe bice bigize pepsinogen?
Pepsinogens igizwe numuyoboro umwe wa polypeptide ufite uburemere bwa molekile hafi 42.000 Da. Pepsinogène ikomatanyirizwa hamwe kandi ikarekurwa cyane cyane na selile nkuru yigifu yo mu gifu cyumuntu mbere yo guhindurwa muri proteolytic enzyme pepsin, ikaba ari ingenzi cyane mubikorwa byigifu.
3.Ni irihe tandukaniro riri hagati ya pepsin na pepsinogen?
Pepsin ni enzyme yo mu gifu ikora igogora poroteyine ziboneka mu biryo byinjiye. Ingirabuzimafatizo zikomeye zisohora pepsin nka zymogene idakora yitwa pepsinogen. Uturemangingo twa parietal mu gifu turimo aside hydrochloric igabanya pH yigifu.

Igikoresho cyo gusuzuma kuri Pepsinogen I / PepsinogenII (Fluorescence Immuno Assay)ni fluorescence immunochromatographic assay kugirango igaragaze ingano ya PGI / PGII muri serumu yumuntu cyangwa plasma, Ikoreshwa cyane mugusuzuma imikorere ya selile ya gastric oxydeque na gastric fundus mucinous gland indwara mubuvuzi.

Murakaza neza kugirango mubone ibisobanuro birambuye.