INCAMAKE

Nka poroteyine ikaze, serumu amyloide A ni poroteyine za heterogeneous z'umuryango wa apolipoprotein,
ifite uburemere bwa molekuline bugereranije. 12000. Cytokine nyinshi igira uruhare mugutunganya imvugo ya SAA
mu gisubizo gikaze. Bitewe na interleukin-1 (IL-1), interleukin-6 (IL-6) hamwe nikibyimba cya niyose-α
(TNF-α), SAA ikomatanyirizwa hamwe na macrophage ikora na fibroblast mu mwijima, ifite ubuzima bucye bwa kabiri gusa
hafi iminota 50. SAA ihuza lipoprotein (HDL) yuzuye mu maraso byihuse iyo ikozwe mu mwijima, iyo
ikeneye guteshwa agaciro na serumu, ubuso bwakagari na protease zo mu nda. Mugihe habaye bimwe bikaze kandi bidakira
gutwika cyangwa kwandura, igipimo cyo kwangirika kwa SAA mumubiri biragaragara ko gahoro mugihe synthesis yiyongera,
biganisha ku kuzamuka guhoraho kwa SAA mumaraso. SAA ni poroteyine ikaze kandi ikongora
marikeri ikomatanya na hepatocytes. SAA yibanze mumaraso biziyongera mumasaha abiri
kubaho k'umuriro, hamwe na SAA kwibandaho biziyongera inshuro 1000 mugihe gikaze
gutwika. Kubwibyo, SAA irashobora gukoreshwa nkikimenyetso cyerekana kwandura mikorobe cyangwa ibicanwa bitandukanye, aribyo
irashobora koroshya gusuzuma indwara no gukurikirana ibikorwa byo kuvura.

Igikoresho cyacu cyo gusuzuma kuri Serumu Amyloide A (Fluorescence Immunochromatographic Assay) irakoreshwa muburyo bwa vitro quantité ya antibody kuri serumu amyloide A (SAA) muri serumu yumuntu / plasma / icyitegererezo cyamaraso yose, kandi ikoreshwa mugupima ubufasha bwumuriro ukabije kandi udakira cyangwa kwandura.

Murakaza neza kubariza amakuru arambuye niba ufite inyungu.