Kanseri y'amaraso

Kanseri y'ibara (CRC, harimo na kanseri y'imboneragara hamwe na kanseri ya colon) ni imwe mu icumbi risanzwe rya tract ya Gastrointestinal.

Kanseri ya Gastrointestinal yabaye "umwicanyi wa mbere w'igihugu, ahagana mu gihugu cya mbere cy'abarwayi ba kastrointestinal babaye mu Bushinwa, naho 60% hagati kandi bitinze.

Utitaye ku rubanza rushya cyangwa impfu, umubare rusange wa kanseri ya Gastrointestinal yarengeje kanseri y'ibihaha. Kanseri yinyama nizo zakira byoroshye kuri kanseri zose zinyuze mu buryo bwo hambere. Nibishishwa byambere byabantu kugirango batsinde kanseri. 5% gusa bya kanseri yubushinwa gusa basuzumwe hakiri kare, naho 60-70% byabarwayi bafite kanseri yububiko nkaho bafite lymph node cyangwa metastand. Igipimo cyo kwisubiraho cyari hejuru ya 30%.

Ubuyapani na Koreya y'Epfo nabo ni ibihugu bifite kanseri ya gastrointestinal, ariko igipimo cyabo cya mbere ni 50-60%, kandi abarenga 90% barenga 90% barashobora gukira. Ubushakashatsi bwo mu Gihugu nubuhanga byerekana ko ingamba zo gusuzuma kanseri yububiko zishobora kugabanya ibyangiritse ndetse impfu za kanseri yububiko.

Mu myaka yashize, usibye Uburayi, Amerika y'Amajyaruguru, Ubuyapani, Singapore, Koreya y'Epfo, Tayiwa, na Hong Kong, habaye guverinoma iyobowe na leta. Kugaragaza hakiri kare kugirango usuzume kanseri ya Gastrointestinal ifite amahirwe yo gukira rwose, hamwe nubusobanuro bukomeye bwimibereho namasoko.

Ibibaho bya kanseri yububiko ni inzira ndende. Kuva muri polyps kugera hyperplasia idasanzwe muri kanseri, mubisanzwe ifata igihe kirekire, itanga igihe cyo kugenzura kanseri yububiko. Kuvura neza no kuvura hakiri kare birashobora kugabanya ibibazo bya kanseri kugeza 60% hamwe nimpfu kuri 80%.

2, ubusobanuro bwa calprotectin mubikorwa byo gukora icyumba

Calprotectin ni poroteyine-zinc-guhambira kuri neutrophile na macrophages, uburemere bwa asrodimer bwa 36.000, umutsimbe wakozwe nishyirahamwe ritari muri MRP14 na S100. Protein.

Binyuze mu bitabo byinshi by'ubushakashatsi hamwe no kugenzura amashusho, Calprotective ifite ubushishozi bwo kumenya kanseri y'amaraso kandi ntabwo yibasiwe n'igituba, ishobora kuboneka mu gihe cya kare kandi kidasanzwe. Irashobora gukoreshwa nkigishushanyo mbonera cya kanseri yububiko.

Kwiyumvira kwa fecal calprotectin, ikizamini cyamaraso cya fecal na Serum CEA kuri kanseri y'amabara yari 88.51%, 83.9,91% na 44.83%. Igipimo cyiza cyamaraso ya fecal na serumu chasa ku barwayi d na stage a yari munsi yicyiciro cyiza cya fecal calprotectin mubarwayi bafite ibyiciro bitandukanye bya Abatware.

Kwiyumvisha kwa fecal calprotectin kuri kanseri yuruvange bwageze kuri 92.7%, kandi agaciro kateganijwe ka NPV kageze kuri 98,6%. Fecal calprotectin ya kanseri yububiko, ≥10mm ibara rya polyps agaciro keza ko guhanura NPV yageze kuri 97.2%.

Kugeza ubu, ibihugu birenga 20 nka Amerika, Ubwongereza, Ubufaransa, Ubufaransa, Ubudage, n'Ubusuwisi bwakoresheje Calprotectin mu buryo bwo gusuzuma indwara na kanseri y'indwara nyinshi, kandi hasuzumwa inyangamugayo indwara y'umutwe. Ibimenyetso bifatika kandi bikiza bikoreshwa cyane mubikorwa byubuvuzi.

3, ibyiza bya calproppin napfumu no guhitana amagambo ahujwe no gusuzuma indwara yinyuma

1. Biroroshye gukora: icyitegererezo kimwe, ibisubizo byinshi byikizamini
2. Ntabwo yongera ingorane zo gukora nigiciro cyigikoresho: igikoresho gishyirwaho, kandi ibikoresho bifite agaciro habisabwa.
3. Densitivite yo hejuru kandi yihariye: Inderumbu yo gutwika, Gastrointestinal kuva amaraso
4. Kugaragaza kare mbere: Ongera amahirwe yo gusuzuma Adencarcinoma na Polyps
5. Igiciro gito cyo kumenya, birashobora gukoreshwa nkibijyanye na colonoscopy
6. Kwihangana: Kugenzura buri mwaka

Ibimenyetso bisanzwe bya kanseri yububiko:

Gutwika munda - Calprotectin, umutware icyiciro nicyiciro abarwayi ba A na B hamwe na stal stal of the stal of the stal, igipimo cyicyiciro cyinshi cyumurwayi, igipimo cyicyiciro gitandukanye cyinshi

Gusiba Gastrointestinal - Amaraso yubupfumu, Sershin. Gustastrointestinal hemorrhage bivuga kubura amaraso munzira ya gastrointestinal kubwimpamvu zitandukanye. Impamvu zisanzwe zirimo gutwika traclation ubwayo, ibyangiritse bya mashini, indwara yuzuye, ikibyimba, hamwe nindwara zo kureba mu matsiko. Ikizamini cyamaraso nicyo gisanzwe kandi cyingenzi cyo gusuzuma amaraso ya Gastrointestinal.

4, uburyo bwo kumenya fecal calprotectin

Ibizamini byacu bya Calproptectin (uburyo bwa zahabu bwa colloidal) burashobora gukoreshwa wenyine kuri kimwe cya kabiri cyo kumenya calprotectin mubyitegererezo byabantu. Irashobora kandi gukoreshwa hamwe nurukurikirane rwa Wiz rwa Imyungosay.

Calprotectin assay ibikoresho (fluorescence imyumechromatography) irashobora kugera kubyemera, indangagaciro zumubare zumubare, hamwe nurwego rwagutse, kugirango tugere ku ngaruka zo gutandukanya indwara zo munda.

Ubupfumu bwamaraso bwamaraso (Colloidal Uburyo bwa Zahabu) bukoreshwa mukumenya neza hemoglobine muntu wa muntu wa muntu, bikwiranye no gusuzuma kuva kera.