Interleukin-6 ni polypeptide igizwe n'iminyururu ibiri ya glycoproteine, ifite uburemere bwa 130kd. Nkumunyamuryango wingenzi wurusobe rwa cytokine, interleukin-6 (IL-6) igira uruhare runini mugukara gukabije, kandi irashobora guhuza ibyiciro bikaze byumwijima, kandi bigatera umusaruro wa poroteyine C-reaction (CRP) na fibrinogen. Indwara nyinshi zandura zishobora gutuma izamuka rya serumu IL-6, kandi urwego rwa IL-6 rufitanye isano rya hafi n’ibisubizo by’abarwayi. Nka cytokine ya pleiotropique ifite ibikorwa byinshi, IL-6 isohorwa na selile T, selile B, phagocyte monon nuclear, na selile endothelia, kandi nikintu cyingenzi cyumuyoboro wumuhuza. Mugihe habaye reaction yumuriro, IL-6 yakozwe mbere, itera umusaruro wa CRP na procalcitonine (PCT) nyuma yo kuyikora. Bizakorwa vuba mugihe cyanduye, ibikomere byimbere ninyuma, kubaga, reaction yo guhangayika, urupfu rwubwonko, tumorigenez, hamwe nuburyo bukabije bwo gutwika ibintu mubindi bihe. IL-6 igira uruhare mu kubaho no gutera indwara nyinshi, urwego rwamaraso rufitanye isano rya bugufi no gutwika, kwandura virusi n'indwara ya autoimmune, kandi impinduka zayo zibaho hakiri kare CRP. Nk’ubushakashatsi bwakozwe, urwego rwa IL-6 rwiyongera vuba nyuma yo kwandura bagiteri, urwego rwa PCT rwiyongera nyuma ya 2h, mugihe CRP yiyongera vuba nyuma ya 6h. Ururenda rudasanzwe cyangwa imvugo ya IL-6 irashobora gutuma habaho indwara zitandukanye, umubare munini wa IL-6 urashobora gusohoka mu maraso mu miterere y’indwara, kandi kumenya IL-6 bifite akamaro kanini mu gusuzuma indwara no guca imanza zitamenyekana.