Helicobacter Pylori (H.pylori) infection is associated with chronic gastritis, gastric ulcer, gastric adenocarcinoma and gastric mucus-associated lymphoma closely. H. Pylori infection rates are about 90% in patients with gastritis, gastric ulcer, duodenal ulcer, and gastric cancer. The World Health Organization has classified H. Pylori as a category 1 carcinogen, specifically listed as gastric cancerRisk factors. H. Pylori detection is an important method for the diagnosis of H.pylori infection