Mycoplasma pneumoniae ndizomwe zimayambitsa matenda amtundu wa kupuma, makamaka kwa ana ndi achinyamata. Mosiyana ndi tizilombo toyambitsa matenda, M. pneumoniae ilibe khoma la selo, zomwe zimapangitsa kuti zikhale zapadera komanso zovuta kuzizindikira. Njira imodzi yodziwika bwino yodziwira matenda obwera chifukwa cha bakiteriyayi ndikuyesa ma antibodies a IgM.

Ma antibodies a IgM ndi ma antibodies oyamba opangidwa ndi chitetezo chamthupi poyankha matenda. Munthu akadwala Mycoplasma pneumoniae, thupi limayamba kupanga ma antibodies a IgM mkati mwa sabata imodzi kapena ziwiri. Kukhalapo kwa ma antibodies amenewa kungakhale chizindikiro chofunikira cha matenda omwe akugwira nawo ntchito chifukwa amayimira kuyankha koyambirira kwa chitetezo cha mthupi.

Kuyeza ma antibodies a IgM ku M. pneumoniae nthawi zambiri kumachitika poyesa serological. Mayeserowa amathandiza kusiyanitsa matenda a M. pneumoniae ndi tizilombo toyambitsa matenda topuma, monga mavairasi kapena mabakiteriya monga Streptococcus pneumoniae. Kuyeza kwabwino kwa IgM kumatha kuthandizira kuzindikira kwa chibayo cha atypical, chomwe nthawi zambiri chimadziwika ndi kuyambika kwapang'onopang'ono kwazizindikiro, kuphatikiza chifuwa chosalekeza, kutentha thupi, komanso kukomoka.

Komabe, zotsatira za antibody za IgM ziyenera kutanthauziridwa mosamala. Zotsatira zabodza zimatha kuchitika, ndipo nthawi yoyezetsa ndiyofunikira. Kuyesedwa koyambirira kwambiri kumatha kubweretsa zotsatira zoyipa chifukwa ma antibodies a IgM amatenga nthawi kuti apange. Choncho, madokotala nthawi zambiri amaganizira mbiri yachipatala ya wodwalayo ndi zizindikiro zake pamodzi ndi zotsatira za labotale kuti amudziwe bwino.

Pomaliza, kuyezetsa ma antibodies a M. pneumoniae IgM kumagwira ntchito yofunika kwambiri pozindikira matenda opuma. Kumvetsetsa kuyankha kwa chitetezo chamthupi kungathandize othandizira azaumoyo kupereka chithandizo chanthawi yake komanso choyenera, pomaliza kuwongolera zotsatira za odwala. Pamene kafukufuku akupitilira, titha kudziwa zambiri za ntchito yomwe ma antibodieswa amagwira polimbana ndi matenda opuma.