I roto i te ao tiaki hauora ārai mate, kua roa te whakanuia o te waikawa folic (huaora B9) mō tōna tūranga nui, inā koa mō te hauora o ngā whaea me ngā tamariki. Heoi, ko ngā whanaketanga hou me ngā rangahau nui mai i Hanuere 2026 kei te huri i te māramatanga o te hapori hauora mō te pehea me te wā e whakamātautau ai mō tēnei matūkai nui. E whakaatu ana ngā purongo i tētahi nekehanga nui mai i te whakamātautau folate pūtau toto whero (RBC) noa ki ngā tikanga toto toto tika ake, me te hura i tētahi rohe hou, motuhake i roto i te whakamātautau tātaritanga.

Te Neke Atu i te Whakamātautau RBC Folate

Mō ngā tekau tau, i whakaarohia te whakamātautau folate RBC hei taputapu paerewa hei ine i ngā toa folate roa i roto i te tinana. Heoi, kei te neke haere ngā aratohu hauora matua i tēnei mahi. I roto i tētahi aratohu haumanu hou i whakahoutia mai i Anthem, i whakaputaina i te 6 o Hānuere, 2026, e kī ana **kāore te whakamātautau waikawa folic RBC i te "mea e hiahiatia ana i ngā wā katoa"**. E whakanui ana te aratohu kua puta ake te whakamātautau folate toto hei aromatawai tika ake, pono ake, me te paerewa ake o te tūnga folate o nāianei.

Ko te take i muri i tēnei panonitanga e ahu mai ana i te whai huatanga haumanu me te angitu hauora tūmatanui. Mai i te wā i whakahaua ai te whakapakari i ngā hua witi ki te waikawa folic i te United States i te tau 1998, kua noho te korenga folate nui haumanu hei "huihuinga onge," me te hekenga o ngā reiti korenga mai i te 18.3% ki raro iho i te 0.2%. Hei tāpiri, e whakaatu ana ngā taunakitanga he nui ngā herenga tikanga o ngā whakamātautau folate RBC, tae atu ki te kore o te paerewa, te rerekētanga hangarau, me te ngawari ki ngā hapa i roto i te whakarite tauira. He maha ngā rangahau kua whakaū kāore he mōhiohio e tika ana mai i ngā taumata folate RBC i tua atu i te mea e tukuna ana e te whakamātautau folate serum ngawari, ka waiho te mea tuatahi hei kōwhiringa koretake me te iti ake te pono i roto i te mahi haumanu hou.

E tautokona ana tēnei ia o te ao tūturu e tētahi rangahau whakamuri nui mai i Te Whare Wānanga o Uppsala i Huitene, i whakaputaina ki *Biomedicines* i te 9 o Hānuere, 2026. I te tātari i ngā inenga folate neke atu i te 578,000 mai i te tau 2005 ki te 2024, i kitea e te rangahau ahakoa kua piki ake ngā taumata folate plasma i roto i ngā tekau tau e rua, ka taea e te whakawhiti i waenga i ngā tūāpapa tātari rerekē te whakaputa i ngā panonitanga tikanga. E whakaatu ana tēnei i te hiranga o te tirotiro tonu i ngā tau waenga o ngā biomarker hei kite i te nekehanga tātari me te aroturuki i ngā ia kai mō te wā roa, hei tautoko anō i te hiahia mō ngā tikanga whakamātautau paerewa, tika.

Te Hiranga Tuturu o te Folate i te Wā Hapūtanga

Ahakoa te whanaketanga o ngā tikanga whakamātautau, kāore anō kia tautohetia te hiranga taketake o te folate, inā koa i te wā e hapu ana. I roto i tētahi rangahau tirohanga whakamua i whakaputaina i roto i te *Tzu Chi Medical Journal* i te 21 o Hānuere, 2026, i whakaū i ngā hua kino o te korenga o te folate i te wā e hapu ana. I kitea i roto i te rangahau, i tirotirohia ai te 351 o ngā kaiuru, **he nui ake te mōrearea o ngā hua kino ki ngā tāngata hapu he iti ake te taumata o te waikawa folic, tae atu ki ngā whānautanga o mua (16.94% i roto i te rōpū taumata iti) me te aukati i te tipu o te kukune (27.11% i roto i te rōpū taumata iti, ki te whakaritea ki te 13.38% i roto i te rōpū taumata teitei). I whakatau ngā kairangahau he mea nui te piri ki ngā taunakitanga kai mō te tāpiringa waikawa folic hei ārai i ēnei raruraru.

E tautoko ana ēnei taunakitanga haumanu i ngā kaupapa hauora tūmatanui e haere tonu ana. Hei tauira, ko ngā kaupapa hauora ā-rohe, pērā i te kete ratonga "Xiang series" i Changsha, Haina, kei te whakauru i te tāpiringa waikawa folic me te aratohu ki roto i ngā mekameka tiaki whānui "mai i mua i te hapūtanga ki muri i te whānautanga", e whakaatu ana i te whakapau kaha o te ao ki tēnei mahi ārai matua.

He Rohe Hou: Te Whakamātautau Tātaritanga mō te Ngongo Folate

Ko te rongo hou pea i te marama o Hānuere 2026 ko te nekehanga ki te tātaritanga ehara i te mea ko ngā taumata folate anake, engari ko te kaha o te tinana ki te whakamahi i te folate e whiwhi ana. I te 12 o Hānuere, i panuitia e Micoy Therapeutics kua whakawhiwhia tana NeuroLume™ Test ki te Breakthrough Device Designation e te US Food and Drug Administration (FDA). Ka kitea e tēnei whakamātautau hou, i te wā tiaki, te aroaro o ngā folate receptor alpha autoantibodies (FRAA), ka taea te aukati i te kawe o te folate ki roto i ngā kiko.

He panonitanga tauira tēnei. Ka inehia e ngā whakamātautau toto, toto rānei te nui o te folate i roto i te toto, engari kāore e taea te whakamārama he aha pea he ngoikore te folate mahi a te tangata ahakoa te nui o te kai, te tāpiringa rānei. Kua hangaia te Whakamātautau NeuroLume hei whakamahi mā ngā pakeke me ngā tamariki e arotakehia ana mō te ngoikore o te folate kāore i whakamāramatia, te anemia macrocytic, ngā āwangawanga whanaketanga rānei e whakapaetia ana he ngoikore te kawe folate. Ko tēnei putanga hou, e tautokona ana e ngā tekau tau o te rangahau taketake, e oati ana ki te whakarato i ngā mōhiohio tikanga kāore i hopukina e ngā inenga folate pūnaha paerewa, ka taea te whakatuwhera i ngā māramatanga hou mō ngā āhuatanga mai i te kore tamariki ki ngā mate whanaketanga roro.

Hei whakamutunga, ko ngā purongo o Hānuere 2026 e whakaatu ana i tētahi āhua o tētahi mara e pakeke haere ana. Kei te ngāwari haere, kei te tika haere hoki ngā tirotiro auau me te hekenga o ngā whakamātautau toto whero me te hiahia ki ngā whakamātautau toto. Kei te whakamanahia tonutia te hiranga o te folate mō ngā putanga hauora o te hāputanga e ngā rangahau hou. Ko te mea tino whakahihiri, kei te whānui haere te mara ki ngā tātaritanga motuhake ka taea te whakaoti i te panga o ngā mate e pā ana ki te folate i te taumata pūtau, e tuku ana i te tumanako hou mō ngā tūroro kua hinga i roto i ngā kapiti o te whakamātautau tuku iho.