Ngwa ule a dabara adaba maka nchọpụta ọnụọgụ nke adrenocorticotropic hormone (ATCH) na nlele Plasma nke mmadụ na Vitro, nke a na-ejikarị eme nchọpụta inyeaka nke ACTH hypersecretion, ACTH kwụụrụ onwe ya na-emepụta hypopituitar anụ ahụ pituitary na ụkọ ACTH na ọrịa ectopic ACTH. A ga-enyocha ya na ozi gbasara ahụike ndị ọzọ.