Nchịkọta

Dị ka nnukwu protein nke oge, serum amyloid A bụ nke protein dị iche iche nke ezinụlọ apolipoprotein, nke
nwere ikwu molekụla arọ nke ihe ruru. 12000. Ọtụtụ cytokines na-etinye aka na nhazi nke okwu SAA
na nnukwu usoro nzaghachi. Ihe na-akpali akpali site na interleukin-1 (IL-1), interleukin-6 (IL-6) na tumor necrosis factor-α.
(TNF-α), SAA na-arụ ọrụ site na macrophages na-arụ ọrụ na fibroblast na imeju, nke nwere obere ọkara ndụ nke naanị.
gburugburu 50 nkeji. SAA na-ejikọta lipoprotein dị elu (HDL) n'ọbara ngwa ngwa na njikọ nke imeju.
kwesịrị iweda ya site na serum, elu cell na proteases intracellular. N'ihe banyere ụfọdụ nnukwu na-adịghị ala ala
mbufụt ma ọ bụ ọrịa, nbibi nke SAA n'ime ahụ doro anya na-ebelata ka njikọ na-abawanye,
nke na-eduga na ịrị elu na-aga n'ihu na SAA itinye uche na ọbara. SAA bụ protein na-agba ọsọ na mkpali
akara nke synthesized site hepatocytes. Ntinye uche SAA n'ọbara ga-abawanye n'ime awa ole na ole
ọnọdụ nke mbufụt, na itinye uche SAA ga-enwe mmụba ugboro 1000 n'oge nnukwu
mbufụt. Ya mere, SAA nwere ike iji dị ka ihe na-egosi microbial ọrịa ma ọ bụ dị iche iche inflammations, nke
nwere ike ikwado nchoputa nke mbufụt na nlekota oru ọgwụgwọ.

Ngwa nyocha anyị maka Serum Amyloid A (Fluorescence Immunochromatographic Assay) na-adabara na nchọpụta ọnụọgụ nke antibody na serum amyloid A (SAA) na ọbara mmadụ / plasma / ọbara dum, a na-eji ya maka nyocha inyeaka nke nnukwu mbufụt na-adịghị ala ala ma ọ bụ ọrịa.

Nabata na ịkpọtụrụ maka nkọwa ndị ọzọ ma ọ bụrụ na ị nwere mmasị.