Ngwa nyocha maka Calprotectin (cal) bụ a colloidal gold immunochromatographic assay maka ọkara nke mkpebi siri ike nke cal sitere na nsị mmadụ, nke nwere nchọpụta ngwa dị mkpa.
uru maka ọrịa afọ ọzịza. Nnwale a bụ reagent nyocha. Ihe nlele niile dị mma ga-abụrịrị
kwadoro site na usoro ndị ọzọ. Ezubere ule a maka naanị ndị ọkachamara ahụike.
Ka ọ dị ugbu a, a na-eji ule a eme ihe maka IVD, ọ dịghị mkpa ọzọ ngwá ọrụ.
Nchịkọta
Cal bụ heterodimer, nke mejupụtara MRP 8 na MRP 14. Ọ dị na cytoplasm neutrophils.
ma gosipụta ya na akpụkpọ anụ mononuclear. Cal bụ protein na-agba agba, ọ nwere ihe kwụsiri ike
N'ihe dị ka otu izu n'ime afọ mmadụ, a na-ekpebi na ọ ga-abụ akara nrịanrịa na-egbuke egbuke.
Ngwa ahụ bụ ule dị mfe, nke na-achọpụta ihe dị n'ime afọ mmadụ, ọ nwere nchọpụta dị elu.
uche na ike kpọmkwem. Nnwale ahụ dabere na sanwichi ọgwụ mgbochi abụọ dị elu
ụkpụrụ mmeghachi omume na ọla edo immunochromatographic assay analysis technics, ọ nwere ike inye nsonaazụ
n'ime nkeji iri na ise.
Ụkpụrụ nke usoro
The warara nwere mgbochi cal mkpuchi McAb na ule mpaghara na ewu mgbochi oke bekee IgG mgbochi na njikwa
mpaghara, nke a na-agbanye na chromatography akpụkpọ ahụ n'ọdịnihu. A na-eji akwa mkpuchi akwa akwa kpuchie ya
ọla edo colloidal akpọrọ mgbochi cal McAb na ọla edo colloidal akpọrọ oke bekee IgG mgbochi n'ihu.
Mgbe a na-anwale nlele dị mma, cal dị na sample bịara na ọla edo colloidal nke akpọrọ anti cal McAb,
ma na-etolite mgbagwoju anya nke na-alụso ọrịa ọgụ, dịka a na-ahapụ ya ka ọ kwaga n'akụkụ eriri ule, cal conjugate
A na-ejide mgbagwoju anya site na mkpuchi mgbochi cal McAb na akpụkpọ ahụ wee mepụta "mkpuchi mgbochi cal
McAb-cal-colloidal ọla edo akpọrọ anti cal McAb' complex, otu agba ule nwere agba pụtara na ule.
mpaghara. Agba agba na-ejikọta nke ọma na ọdịnaya cal. Ihe nlele na-adịghị mma adịghị
mepụta eriri ule n'ihi enweghị mgbagwoju anya colloidal gold conjugate cal. N'agbanyeghị cal
dị na sample ma ọ bụ na ọ bụghị, enwere eriri uhie na-apụta na mpaghara ntụaka yana njikwa mma
mpaghara, nke a na-ahụta dị ka ụkpụrụ ụlọ ọrụ ime ụlọ dị mma.
Nnwale CAL anyị bụ ụlọ ọrụ mbụ iji nweta CFDA na China. Anyị na-ebufelarị ọtụtụ mba na nzaghachi dị mma.
Nabata ịkpọtụrụ anyị maka nkọwa ndị ọzọ.
Oge nzipu: Sep-28-2022