Pepsinogen Kuvyog tsim thiab tso tawm los ntawm cov hlwb tseem ceeb ntawm thaj tsam oxyntic glandular ntawm lub plab, thiab pepsinogen II yog tsim thiab tso tawm los ntawm thaj tsam pyloric ntawm lub plab. Ob qho tib si raug qhib rau pepsins hauv lub plab lumen los ntawm HCl uas tso tawm los ntawm cov hlwb fundic parietal.

1. Pepsinogen II yog dab tsi?
Pepsinogen II yog ib qho ntawm plaub hom aspartic proteinases: PG I, PG II, Cathepsin E thiab D. Pepsinogen II feem ntau yog tsim tawm hauv Oxyntic gland mucosa ntawm lub plab, lub gastric antrum thiab duodenum. Nws yog secreted feem ntau rau hauv lub gastric lumen thiab mus rau hauv kev ncig.
2. Cov khoom xyaw ntawm pepsinogen yog dab tsi?
Cov Pepsinogens muaj ib txoj saw polypeptide nrog qhov hnyav molecular ntawm kwv yees li 42,000 Da. Pepsinogens yog synthesized thiab secreted feem ntau los ntawm cov hlwb gastric chief ntawm tib neeg lub plab ua ntej hloov mus rau hauv proteolytic enzyme pepsin, uas yog qhov tseem ceeb rau cov txheej txheem zom zaub mov hauv plab.
3. Qhov txawv ntawm pepsin thiab pepsinogen yog dab tsi?
Pepsin yog ib qho enzyme hauv plab uas ua haujlwm los zom cov protein uas pom muaj nyob rau hauv cov khoom noj uas noj. Cov hlwb hauv plab tso tawm pepsin ua ib qho zymogen tsis ua haujlwm hu ua pepsinogen. Cov hlwb parietal hauv daim ntaub plab tso tawm hydrochloric acid uas txo qis pH ntawm lub plab.

Cov Khoom Siv Kuaj Mob rau Pepsinogen I / PepsinogenII (Fluorescence Immuno Assay)yog ib qho kev ntsuam xyuas fluorescence immunochromatographic rau qhov kev ntsuas kom paub ntau ntawm PGI / PGII hauv tib neeg cov ntshav lossis plasma, Nws yog siv los ntsuam xyuas kev ua haujlwm ntawm lub plab zom mov oxyntic gland thiab gastric fundus mucinous gland kab mob hauv kev kho mob.

Txais tos hu rau kom paub meej ntxiv.