Pepsinogen Iyog synthesized thiab secreted los ntawm cov thawj hlwb ntawm lub oxyntic glandular cheeb tsam ntawm lub plab, thiab pepsinogen II yog synthesized thiab secreted los ntawm lub pyloric cheeb tsam ntawm lub plab. Ob leeg yog qhib rau pepsins nyob rau hauv lub plab lumen los ntawm HCl secreted los ntawm fundic parietal hlwb.

1.Pepsinogen II yog dab tsi?
Pepsinogen II yog ib qho ntawm plaub aspartic proteinases: PG I, PG II, Cathepsin E thiab D. Pepsinogen II yog tsim nyob rau hauv Oxyntic gland mucosa ntawm lub plab, plab antrum thiab duodenum. Nws yog secreted mas nyob rau hauv lub plab lumen thiab mus rau hauv kev.
2.Dab tsi yog cov khoom ntawm pepsinogen?
Pepsinogens muaj xws li ib tug tib polypeptide saw nrog ib tug molecular luj ntawm kwv yees li 42,000 Da. Pepsinogens yog synthesized thiab secreted feem ntau los ntawm lub plab hnyuv loj hlwb ntawm tib neeg lub plab ua ntej hloov mus rau hauv lub proteolytic enzyme pepsin, uas yog ib qho tseem ceeb rau digestive dab nyob rau hauv lub plab.
3.Dab tsi yog qhov txawv ntawm pepsin thiab pepsinogen?
Pepsin yog lub plab enzyme uas ua haujlwm rau zom cov protein uas pom hauv cov zaub mov noj. Gastric Chief cells secrete pepsin ua ib qho tsis muaj zog zymogen hu ua pepsinogen. Parietal hlwb nyob rau hauv lub plab hauv ob sab phlu secrete hydrochloric acid uas txo cov pH ntawm lub plab.

Diagnostic Kit rau Pepsinogen I / PepsinogenII (Fluorescence Immuno Assay)yog ib qho fluorescence immunochromatographic assay rau kev kuaj kom muaj nuj nqis ntawm PGI / PGII nyob rau hauv tib neeg cov ntshav los yog ntshav, Nws yog siv los ntsuas lub plab oxyntic gland cell function thiab gastric fundus mucinous gland kab mob hauv chaw kho mob.

Txais tos tiv tauj kom paub meej ntxiv.