YUAV TSUM SIV LI CAS

Cov Khoom Siv Kuaj Mob rau Calprotectin (cal) nws yog ib qho kev ntsuas kub colloidal immunochromatographic rau kev txiav txim siab semiquantitative ntawm cal los ntawm tib neeg cov quav, uas muaj cov khoom siv tseem ceeb rau kev kuaj mob
muaj txiaj ntsig rau kab mob plab hnyuv. Qhov kev kuaj no yog ib qho tshuaj ntsuam xyuas. Txhua tus qauv kuaj pom zoo yuav tsum tau
tau lees paub los ntawm lwm txoj kev. Qhov kev xeem no tsuas yog rau cov kws kho mob siv xwb.
Lub caij no, qhov kev xeem no yog siv rau IVD, tsis tas yuav muaj cov cuab yeej ntxiv.
LUS QHIA
Cal yog ib qho heterodimer, uas yog tsim los ntawm MRP 8 thiab MRP 14. Nws muaj nyob rau hauv neutrophils cytoplasm
thiab qhia tawm ntawm cov hlwb mononuclear. Cal yog cov protein theem mob, nws muaj qhov ruaj khov zoo
theem li ib lub lim tiam hauv tib neeg cov quav, nws raug txiav txim siab tias yog ib qho cim qhia txog kab mob plab hnyuv.
Cov khoom siv no yog ib qho kev kuaj yooj yim, pom tau ib nrab zoo uas ntes tau cov cal hauv tib neeg cov quav, nws muaj kev ntes tau zoo
kev rhiab heev thiab muaj zog tshwj xeeb. Qhov kev xeem raws li kev tshwj xeeb siab ob chav tshuaj tiv thaiv kab mob sandwich
Cov ntsiab lus ntawm cov tshuaj tiv thaiv thiab cov txheej txheem tshuaj ntsuam kub immunochromatographic, nws tuaj yeem muab qhov tshwm sim
tsis pub dhau 15 feeb.
TSAB NTAWV QHIA TXOG TXHEEJ TXHEEM
Cov kab txaij muaj cov tshuaj tiv thaiv cal McAb ntawm thaj chaw kuaj thiab cov tshuaj tiv thaiv IgG tiv thaiv tshis ntawm kev tswj hwm
thaj tsam, uas yog fastened rau membrane chromatography ua ntej. Lable pad yog coated los ntawm
kub colloidal labeled anti cal McAb thiab kub colloidal labeled luav IgG antibody ua ntej.
Thaum kuaj cov qauv zoo, cov cal hauv cov qauv sib xyaw nrog cov kub colloidal uas muaj cim anti cal McAb,
thiab tsim cov tshuaj tiv thaiv kab mob, vim nws raug tso cai kom mus raws li daim kab kuaj, cov cal conjugate
Cov khoom sib xyaw raug ntes los ntawm cov txheej tiv thaiv cal McAb ntawm daim nyias nyias thiab tsim "cov txheej tiv thaiv cal"
McAb-cal-colloidal kub uas muaj daim ntawv lo rau anti cal McAb” complex, ib txoj kab kuaj xim tau tshwm sim ntawm qhov kev xeem
cheeb tsam. Qhov xim muaj zog zoo sib xws nrog cov ntsiab lus cal. Ib qho qauv tsis zoo tsis
tsim ib txoj kab xeem vim tsis muaj colloidal kub conjugate cal complex. Txawm cal yog
muaj nyob rau hauv cov qauv lossis tsis muaj, muaj ib txoj kab liab tshwm sim ntawm thaj chaw siv thiab kev tswj xyuas zoo
cheeb tsam, uas suav hais tias yog cov qauv kev lag luam sab hauv zoo.

Peb qhov kev xeem CAL yog thawj lub Hoobkas tau txais CFDA hauv Suav teb. Peb twb xa khoom mus rau ntau lub tebchaws nrog txhua qhov kev teb zoo.

Txais tos tiv tauj peb kom paub meej ntxiv.