HOOLAHA

Ma ke ʻano he pūmua acute phase, ʻo serum amyloid A no nā protein heterogeneous o ka ʻohana apolipoprotein, kahi
loaʻa ke kaumaha molekala pili o approx. 12000. Nui nā cytokines i komo i ka hoʻoponopono o ka'ōlelo SAA
i ka pane ʻana o ka pae acute. Hoʻoulu ʻia e interleukin-1 (IL-1), interleukin-6 (IL-6) a me ka tumor necrosis factor-α
(TNF-α), hoʻohui ʻia ʻo SAA e nā macrophages i hoʻāla ʻia a me ka fibroblast i loko o ke ake, nona ka hapalua o ke ola pōkole wale nō.
ma kahi o 50 minuke. Hoʻopaʻa ʻo SAA me ka lipoprotein kiʻekiʻe kiʻekiʻe (HDL) i ke koko me ka wikiwiki i ka hana ʻana i loko o ke ake.
Pono e hoʻohaʻahaʻa ʻia e ka serum, ka ʻili o ka cell a me nā protease intracellular. I ka hihia o kekahi acute a me ka maʻi
ʻo ka ʻāʻī a i ʻole ka maʻi, ka emi ʻana o ka nui o ka SAA i loko o ke kino i ka wā e piʻi ana ka synthesis,
e alakaʻi ana i ka piʻi mau ʻana o ka ʻike SAA i ke koko. ʻO ka SAA kahi protein acute phase a inflammatory
hōʻailona synthesized e nā hepatocytes. E piʻi aʻe ka manaʻo SAA i ke koko i loko o ʻelua mau hola ma hope
ʻO ka hoʻomaka ʻana o ka mumū, a ʻo ka ʻike SAA e ʻike i ka piʻi ʻana o 1000-manawa i ka wā acute
ʻāʻā. No laila, hiki ke hoʻohana ʻia ʻo SAA ma ke ʻano he hōʻailona o ka maʻi microbial a i ʻole nā ​​​​inflammatory like ʻole
hiki ke hoʻomaʻamaʻa i ka hōʻoia ʻana o ka mumū a me ka nānā ʻana i nā hana therapeutic.

ʻO kā mākou Diagnostic Kit for Serum Amyloid A (Fluorescence Immunochromatographic Assay) pili i ka in vitro quantitative detection of antibody to serum amyloid A (SAA) i loko o ke kanaka serum/plasma/holo blood sample, a ua hoʻohana ʻia ia no ka hōʻailona kōkua o ka maʻi ʻeha a i ʻole. maʻi maʻi.

Welina mai e leka uila no nā kikoʻī hou aku inā makemake ʻoe.