C-peptide, a i ʻole ka hoʻopili ʻana i ka peptide, he ʻakika amino kaulahao pōkole e hana nui i ka hana ʻana o ka insulin i loko o ke kino. He huahana ia o ka hana ʻana o ka insulin a hoʻokuʻu ʻia e ka pancreas i ka nui like me ka insulin. ʻO ka hoʻomaopopo ʻana i ka C-peptide hiki ke hāʻawi i nā ʻike koʻikoʻi i nā kūlana olakino like ʻole, ʻoi aku ka maʻi diabetes.

Ke hana ka pancreas i ka insulin, hana mua ia i kahi mole nui i kapa ʻia ʻo proinsulin. Hoʻokaʻawale ka Proinsulin i ʻelua ʻāpana: insulin a me C-peptide. ʻOiai ke kōkua nei ka insulin i ka hoʻoponopono ʻana i nā pae kōpaʻa koko ma o ka hāpai ʻana i ka lawe ʻana o ka glucose i loko o nā cell, ʻaʻohe kuleana kūpono o C-peptide i ka metabolism glucose. Eia nō naʻe, he hōʻailona koʻikoʻi ia no ka loiloi ʻana i ka hana pancreatic.

ʻO kekahi o nā hoʻohana nui no ke ana ʻana i nā pae C-peptide aia i ka maʻi a me ka mālama ʻana i ka maʻi diabetes. I ka poʻe me ka maʻi maʻi type 1, hoʻouka ka ʻōnaehana pale a hoʻopau i nā cell beta e hana ana i ka insulin i loko o ka pancreas, e hopena i nā pae haʻahaʻa a ʻike ʻole ʻia o ka insulin a me C-peptide. I ka hoʻohālikelike ʻana, loaʻa pinepine nā kānaka me ka maʻi maʻi type 2 i nā pae C-peptide maʻamau a kiʻekiʻe paha no ka mea e hana ko lākou kino i ka insulin akā kūpaʻa i kona hopena.

Hiki i nā ana C-peptide ke kōkua i ka hoʻokaʻawale ʻana ma waena o ka maʻi diabetes type 1 a me ke ʻano 2, alakaʻi i nā hoʻoholo lapaʻau, a nānā i ka pono o ka mālama ʻana. No ka laʻana, ʻo ka mea maʻi me ka maʻi maʻi type 1 e loaʻa ana i kahi transplant cell islet e nānā ʻia ko lākou mau pae C-peptide e nānā i ka holomua o ke kaʻina hana.

Ma waho aʻe o ka maʻi maʻi, ua aʻo ʻia ʻo C-peptide no kāna mau hopena palekana i nā ʻano kikoʻī. Manaʻo kekahi mau haʻawina e loaʻa paha i ka C-peptide nā waiwai anti-inflammatory e kōkua i ka hōʻemi ʻana i nā pilikia pili i ka maʻi maʻi, e like me ke aʻalolo a me ka hōʻino ʻana.

I ka hopena, ʻoiai ʻaʻole pili pono ʻo C-peptide i nā pae glucose koko, he biomarker waiwai ia no ka hoʻomaopopo ʻana a me ka mālama ʻana i ka maʻi diabetes. Ma ke ana ʻana i nā pae C-peptide, hiki i nā mea mālama ola ke loaʻa ka ʻike i ka hana pancreatic, hoʻokaʻawale i waena o nā ʻano maʻi diabetes, a hoʻonohonoho i nā hoʻolālā lapaʻau i nā pono pilikino.

Ua loaʻa iā mākou ʻo Baysen MedicalʻO ka pahu hoʻāʻo C-peptide ,ʻO ka pahu hoʻāʻo insulinaHbA1C pahu ho'āʻono ka maʻi diabetes