Interleukin-6 polypeptide ne wanda ya ƙunshi sarƙoƙi na glycoprotein guda biyu, wanda ke da nauyin kwayoyin 130kd. A matsayin wani muhimmin memba na cibiyar sadarwa na cytokine, interleukin-6 (IL-6) yana taka muhimmiyar rawa a cikin mummunan halayen kumburi, kuma yana iya daidaita yanayin halayen hanta, kuma yana ƙarfafa samar da furotin C-reactive (CRP) da fibrinogen. Yawancin cututtuka masu yaduwa na iya haifar da hawan jini a matakin IL-6, kuma matakin IL-6 yana da alaƙa da sakamakon haƙuri. A matsayin cytokine na pleiotropic tare da ayyuka masu yawa, IL-6 yana ɓoye ta hanyar T cell, B cell, mononuclear phagocyte, da kuma cell endothelial, kuma yana da mahimmanci na cibiyar sadarwa mai matsakanci mai kumburi. Bayan abin da ya faru na kumburi, IL-6 ya fara samar da shi, wanda ke haifar da samar da CRP da procalcitonin (PCT) akan samarwa. Za a samar da shi da sauri idan akwai kamuwa da cuta, raunin ciki da na waje, aikin tiyata, halayen danniya, mutuwar kwakwalwa, ciwon tumorigenesis, da kuma mummunan tsarin amsawa na wasu yanayi. IL-6 yana shiga cikin abubuwan da suka faru da ci gaba da cututtuka da yawa, matakin jininsa yana da alaƙa da kumburi, kamuwa da cuta da cututtuka na autoimmune, kuma canje-canje ya faru a baya fiye da CRP. Dangane da sakamakon bincike, matakin IL-6 yana ƙaruwa da sauri akan kamuwa da cuta na kwayan cuta, matakin PCT yana ƙaruwa bayan 2h, yayin da CRP kawai yana ƙaruwa da sauri bayan 6h. Rashin haɓakar ɓarna ko bayyanar cututtuka na IL-6 sau da yawa na iya haifar da aukuwar jerin cututtuka, babban adadin IL-6 za a iya ɓoye cikin jini a cikin yanayin rashin lafiya, kuma gano IL-6 yana da matukar muhimmanci ga ganewar cututtuka da kuma yanke hukunci.